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The sixth edition of the WHO Manual for the Laboratory Examination and Processing of Human Semen is a reference document for procedures and methods for the laboratory examination and processing of human semen, which are intended to maintain and sustainthe quality of analysis and the comparability of results from different laboratories.
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Semen analysis may be useful in both clinical and research settings, for investigating male fertility status as well as monitoring spermatogenesis during and following male fertility regulation and other interventions. This manual provides updated, standardized,evidence-based procedures and recommendations for laboratory managers, scientists and technicians to follow in examining human semen in a clinical or research setting. Detailed protocols for routine, optional and research tests are elaborated.
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Home / Biologicals / Human (other) / Semen / Semen - Normal - Bulk VolumesSemen - Normal - Bulk VolumesCatalogue Number: 991-04-P Print This Page Print SpecificationsDescription Product Name Semen Source Pooled Human Donors Catalogue Number 991-04-P Form Liquid Product Note Pooled from > 3 donors Formulation Raw, unprocessed liquid, non-sterile, without preservatives. Appearance Yellow to white milky, viscous liquid Additional Info This product does not contain cryopreservatives. As a result, it may not contain viable spermatozoa. Custom Collection Inquire at info@leebio.com for custom collections Related Products 991-04-S - Single Human Donor Semen497-11 - Prostate Specific Antigen from human semen498-11 - PSA/ACT Complex antigen Storage -20C Recertification Due to differing stabilities of various biomarkers in this complex biological material it is not possible to assign a single expiration date that is relevant to all biomarkers. The end user should monitor the biomarkers of interest to verify suitability over time. Infectious Disease Testing Negative or non-reactive at the donor level for anti-HIV 1 and 2, anti-HCV and HBsAg by FDA approved methods. Handling - Thaw quickly, in a 37C water bath, removing as soon as thawed.- Centrifuge briefly to ensure complete recovery.- Mix by gentle inversion or trituration. Synonyms Seminal fluid, sperm, spermatozoa, ejaculate, seed, germ, jism ApplicationsDiagnostic Base MatricesOverviewLee Biosolutions collects, validates and certifies pooled donor Semen for medical research and clinical bio-medical manufacturing.
During the process of ejaculation, sperm passes through the ejaculatory ducts and mixes with fluids from the seminal vesicles, the prostate, and the bulbourethral glands to form the semen. The seminal vesicles produce a yellowish viscous fluid rich in fructose and other substances that makes up about 70% of human semen. The prostatic secretion, influenced by dihydrotestosterone, is a whitish (sometimes clear), thin fluid containing proteolytic enzymes, citric acid, acid phosphatase and lipids. The bulbourethral glands secrete a clear secretion into the lumen of the urethra to lubricate it.
View More About Our Company SOLUTIONS CapabilitiesSmall to Large-Scale Antigen Manufacturing
GMP Manufacturing
Assay Development & Validation
Scientific Expertise Across Multiple Specialties
ProductsAntigens & Enzymes
Antibodies & Antisera
Biochemicals
Human Biologicals
ServicesCustom Diagnostic and GMP-grade Manufacturing
Product & assay development
Process Transfer, Validation & Optimization (Contact Us)
Analytical testing & technical support
Prospective biological collections
Learn More About What We IVDo
ORDER How to OrderEmail: orders@medixbiochemica.com
Fax: 866-371-5222
Phone: 314-968-1091
How to Place an Order
Distributors
Contact UsProduct Availability
Technical Support
Bulk Quote Request
Frequent RequestsTerms & Conditions of Sale
Certificate of Analysis
OEM Manufacturing
Customer Satisfaction Survey
Featured Product Low Density Lipoprotein (LDL) Human Plasma 360-10 View All Results SIGN IN Email Password Sign in Forgot Password Don't have an account with us? CREATE ACCOUNT
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Home / Biologicals / Human (other) / Semen / Semen - Normal Samples - Fresh, Never FrozenSemen - Normal Samples - Fresh, Never FrozenCatalogue Number: 991-04-FS Print This Page Print SpecificationsDescription Product Name Semen - Fresh, Never Frozen Source Single Human Donor Catalogue Number 991-04-FS Form Liquid Sample Size 1 donor x > 0.5 mL Donor Race Reported Donor Gender Male Donor Age Reported Donor Medical History Available by request Additional Info Collected upon order - Shipped within 12 hours of collection This product is not sterile and contains to added preservatives. As a result, it may not contain viable spermatozoa. Preservatives None (Available by request) Special Collections Available on request Storage 2-8C or ambient Expiration 3 daysTo extend recertification, freeze or addition of a preservative is recommended. Availability 1-2 day lead time Synonyms Seminal fluid, sperm, spermatozoa, ejaculate, seed, germ, jism ApplicationsOverviewLee Biosolutions is the leading collector and distributor of human biological fluids and tissues for protein isolation, diagnostic manufacturing and medical research. Our laboratory is equipped to handle specific requests for isolation of cells, proteins, pooling requirements or specific aliquots of biological specimens.
Sertoli cells, which nurture and support developing spermatocytes, secrete a fluid into seminiferous tubules that helps transport sperm to the genital ducts. The ductuli efferentes possess cuboidal cells with microvilli and lysosomal granules that modify the semen by reabsorbing some fluid. Once the semen enters the ductus epididymis the principle cells, which contain pinocytotic vessels indicating fluid reabsorption, secrete glycerophosphocholine which most likely inhibits premature capacitation. The accessory genital ducts, the seminal vesicle, prostate glands, and the bulbourethral glands, produce most of the seminal fluid.
Our search revealed that 27 viruses that can result in viremia have been found in human semen (Table). For many of these, data on sexual transmission are lacking. Of these 27 viruses, many cause chronic or latent infection (e.g., HIV virus, cytomegalovirus). However, several cause acute infections, including Lassa fever, Rift Valley fever, and chikungunya viruses. Of those causing acute infections, only Zika and Ebola viruses have been systematically screened for in semen (i.e., in case series or cohort studies rather than case reports). These 27 viruses come from diverse families, suggesting that the presence of many viruses in semen is unlikely to be exclusively dependent on specific or conserved viral epitopes, ability of virus to replicate within the male reproductive tract, or common mechanisms of immune evasion. Other factors that may also influence whether viruses exist in semen are level of viremia, inflammatory mediators (altering blood-barrier permeability), systemic immunosuppression, male reproductive tract immune responses, presence of sexually transmitted diseases, and virus structural stability. In mammals, numerous viruses are detectable in semen, including viruses that can cause disease in humans, such as Japanese encephalitis virus, foot and mouth disease virus, parainfluenza virus, and paravaccinia virus (6). Several other viruses that result in viremia can cause orchitis and have been detected in human testes, suggesting the possibility that these viruses may also be detectable in semen. These viruses include influenza virus, lymphocytic choriomeningitis virus, phlebotomus fever virus, cocksackie B virus, echovirus, dengue virus, systemic acute respiratory syndrome virus, parvovirus, smallpox virus, vaccinia virus, and rubella virus (7). 041b061a72